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BAFF Bispecific Antibodies
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CAT# Product Name Species Reactivity BsAb Type Target 1 Host Animal 1 Target 2 Host Animal 2 INQUIRY
BSDG-H199 Recombinant Human Anti-BAFF x Human Anti-IL17 Bispecific Antibody (Fv-IgG) Human Fv-IgG BAFF Human IL17 Human Inquiry
BSDG-H198 Recombinant Human Anti-BAFF x Human Anti-B7RP1 Bispecific Antibody (Fv-IgG) Human Fv-IgG BAFF Human B7RP1 Human Inquiry
BSDG-019 Recombinant Anti-BAFF x Anti-IL17 Bispecific Antibody (Fv-IgG) Human Fv-IgG BAFF Mouse IL17 Mouse Inquiry
BSDG-018 Recombinant Anti-BAFF x Anti-B7RP1 Bispecific Antibody (Fv-IgG) Human Fv-IgG BAFF Mouse B7RP1 Mouse Inquiry
BABFV-H199 Recombinant Human Anti-BAFF x Human Anti-IL17 Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 BAFF Human IL17 Human Inquiry
BABFV-H198 Recombinant Human Anti-BAFF x Human Anti-B7RP1 Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 BAFF Human B7RP1 Human Inquiry
BABFV-019 Recombinant Anti-BAFF x Anti-IL17 Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 BAFF Mouse IL17 Mouse Inquiry
BABFV-018 Recombinant Anti-BAFF x Anti-B7RP1 Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 BAFF Mouse B7RP1 Mouse Inquiry
FABVC-H199 Recombinant Human Anti-BAFF x Human Anti-IL17 Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc BAFF Human IL17 Human Inquiry
FABVC-H198 Recombinant Human Anti-BAFF x Human Anti-B7RP1 Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc BAFF Human B7RP1 Human Inquiry
FABVC-019 Recombinant Anti-BAFF x Anti-IL17 Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc BAFF Mouse IL17 Mouse Inquiry
FABVC-018 Recombinant Anti-BAFF x Anti-B7RP1 Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc BAFF Mouse B7RP1 Mouse Inquiry
SCDBC-H199 Recombinant Human Anti-BAFF x Human Anti-IL17 Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 BAFF Human IL17 Human Inquiry
SCDBC-H198 Recombinant Human Anti-BAFF x Human Anti-B7RP1 Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 BAFF Human B7RP1 Human Inquiry
SCDBC-019 Recombinant Anti-BAFF x Anti-IL17 Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 BAFF Mouse IL17 Mouse Inquiry
SCDBC-018 Recombinant Anti-BAFF x Anti-B7RP1 Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 BAFF Mouse B7RP1 Mouse Inquiry
BSDBC-H199 Recombinant Human Anti-BAFF x Human Anti-IL17 Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 BAFF Human IL17 Human Inquiry
BSDBC-H198 Recombinant Human Anti-BAFF x Human Anti-B7RP1 Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 BAFF Human B7RP1 Human Inquiry
BSDBC-019 Recombinant Anti-BAFF x Anti-IL17 Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 BAFF Mouse IL17 Mouse Inquiry
BSDBC-018 Recombinant Anti-BAFF x Anti-B7RP1 Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 BAFF Mouse B7RP1 Mouse Inquiry
SCDBF-H199 Recombinant Human Anti-BAFF x Human Anti-IL17 Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc BAFF Human IL17 Human Inquiry
SCDBF-H198 Recombinant Human Anti-BAFF x Human Anti-B7RP1 Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc BAFF Human B7RP1 Human Inquiry
SCDBF-019 Recombinant Anti-BAFF x Anti-IL17 Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc BAFF Mouse IL17 Mouse Inquiry
SCDBF-018 Recombinant Anti-BAFF x Anti-B7RP1 Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc BAFF Mouse B7RP1 Mouse Inquiry
BSFVF-H199 Recombinant Human Anti-BAFF x Human Anti-IL17 Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc BAFF Human IL17 Human Inquiry
BSFVF-H198 Recombinant Human Anti-BAFF x Human Anti-B7RP1 Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc BAFF Human B7RP1 Human Inquiry
BSFVF-019 Recombinant Anti-BAFF x Anti-IL17 Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc BAFF Mouse IL17 Mouse Inquiry
BSFVF-018 Recombinant Anti-BAFF x Anti-B7RP1 Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc BAFF Mouse B7RP1 Mouse Inquiry
BSDBF-H199 Recombinant Human Anti-BAFF x Human Anti-IL17 Bispecific Antibody (Diabody-Fc) Human Diabody-Fc BAFF Human IL17 Human Inquiry
BSDBF-H198 Recombinant Human Anti-BAFF x Human Anti-B7RP1 Bispecific Antibody (Diabody-Fc) Human Diabody-Fc BAFF Human B7RP1 Human Inquiry
BSDBF-019 Recombinant Anti-BAFF x Anti-IL17 Bispecific Antibody (Diabody-Fc) Human Diabody-Fc BAFF Mouse IL17 Mouse Inquiry
BSDBF-018 Recombinant Anti-BAFF x Anti-B7RP1 Bispecific Antibody (Diabody-Fc) Human Diabody-Fc BAFF Mouse B7RP1 Mouse Inquiry
BSTF-H199 Recombinant Human Anti-BAFF x Human Anti-IL17 Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv BAFF Mouse IL17 Mouse Inquiry
BSTF-H198 Recombinant Human Anti-BAFF x Human Anti-B7RP1 Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv BAFF Mouse B7RP1 Mouse Inquiry
BSTF-019 Recombinant Anti-BAFF x Anti-IL17 Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv BAFF Mouse IL17 Mouse Inquiry
BSTF-018 Recombinant Anti-BAFF x Anti-B7RP1 Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv BAFF Mouse B7RP1 Mouse Inquiry
BSCFV-H199 Recombinant Human Anti-BAFF x Human Anti-IL17 Bispecific Antibody (scFv-Fc) Human scFv-Fc BAFF Mouse IL17 Mouse Inquiry
BSCFV-H198 Recombinant Human Anti-BAFF x Human Anti-B7RP1 Bispecific Antibody (scFv-Fc) Human scFv-Fc BAFF Mouse B7RP1 Mouse Inquiry
BSCFV-019 Recombinant Anti-BAFF x Anti-IL17 Bispecific Antibody (scFv-Fc) Human scFv-Fc BAFF Mouse IL17 Mouse Inquiry
BSCFV-018 Recombinant Anti-BAFF x Anti-B7RP1 Bispecific Antibody (scFv-Fc) Human scFv-Fc BAFF Mouse B7RP1 Mouse Inquiry
MNAB-H199 Recombinant Human Anti-BAFF x Human Anti-IL17 Bispecific Antibody (Miniantibody) Human Miniantibody BAFF Mouse IL17 Mouse Inquiry
MNAB-H198 Recombinant Human Anti-BAFF x Human Anti-B7RP1 Bispecific Antibody (Miniantibody) Human Miniantibody BAFF Mouse B7RP1 Mouse Inquiry
MNAB-019 Recombinant Anti-BAFF x Anti-IL17 Bispecific Antibody (Miniantibody) Human Miniantibody BAFF Mouse IL17 Mouse Inquiry
MNAB-018 Recombinant Anti-BAFF x Anti-B7RP1 Bispecific Antibody (Miniantibody) Human Miniantibody BAFF Mouse B7RP1 Mouse Inquiry
BSFC-H199 Recombinant Human Anti-BAFF x Human Anti-IL17 Bispecific Antibody (scFv-CH3) Human scFv-CH3 BAFF Mouse IL17 Mouse Inquiry
BSFC-H198 Recombinant Human Anti-BAFF x Human Anti-B7RP1 Bispecific Antibody (scFv-CH3) Human scFv-CH3 BAFF Mouse B7RP1 Mouse Inquiry
BSFC-019 Recombinant Anti-BAFF x Anti-IL17 Bispecific Antibody (scFv-CH3) Human scFv-CH3 BAFF Mouse IL17 Mouse Inquiry
BSFC-018 Recombinant Anti-BAFF x Anti-B7RP1 Bispecific Antibody (scFv-CH3) Human scFv-CH3 BAFF Mouse B7RP1 Mouse Inquiry
BSCC-H199 Recombinant Human Anti-BAFF x Human Anti-IL17 Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL BAFF Mouse IL17 Mouse Inquiry
BSCC-H198 Recombinant Human Anti-BAFF x Human Anti-B7RP1 Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL BAFF Mouse B7RP1 Mouse Inquiry
BSCC-019 Recombinant Anti-BAFF x Anti-IL17 Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL BAFF Mouse IL17 Mouse Inquiry
BSCC-018 Recombinant Anti-BAFF x Anti-B7RP1 Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL BAFF Mouse B7RP1 Mouse Inquiry
BIBD-H199 Recombinant Human Anti-BAFF x Human Anti-IL17 Bispecific Antibody (Bibody) Human Bibody BAFF Mouse IL17 Mouse Inquiry
BIBD-H198 Recombinant Human Anti-BAFF x Human Anti-B7RP1 Bispecific Antibody (Bibody) Human Bibody BAFF Mouse B7RP1 Mouse Inquiry
BIBD-019 Recombinant Anti-BAFF x Anti-IL17 Bispecific Antibody (Bibody) Human Bibody BAFF Mouse IL17 Mouse Inquiry
BIBD-018 Recombinant Anti-BAFF x Anti-B7RP1 Bispecific Antibody (Bibody) Human Bibody BAFF Mouse B7RP1 Mouse Inquiry
FABFV-H199 Recombinant Human Anti-BAFF x Human Anti-IL17 Bispecific Antibody (Fab-Fv) Human Fab-Fv BAFF Human IL17 Human Inquiry
FABFV-H198 Recombinant Human Anti-BAFF x Human Anti-B7RP1 Bispecific Antibody (Fab-Fv) Human Fab-Fv BAFF Human B7RP1 Human Inquiry
FABFV-019 Recombinant Anti-BAFF x Anti-IL17 Bispecific Antibody (Fab-Fv) Human Fab-Fv BAFF Mouse IL17 Mouse Inquiry
FABFV-018 Recombinant Anti-BAFF x Anti-B7RP1 Bispecific Antibody (Fab-Fv) Human Fab-Fv BAFF Mouse B7RP1 Mouse Inquiry
MiniB-H199 Recombinant Human Anti-BAFF x Human Anti-IL17 Bispecific Antibody (Minibody) Human Minibody BAFF Human IL17 Human Inquiry
MiniB-H198 Recombinant Human Anti-BAFF x Human Anti-B7RP1 Bispecific Antibody (Minibody) Human Minibody BAFF Human B7RP1 Human Inquiry
MiniB-019 Recombinant Anti-BAFF x Anti-IL17 Bispecific Antibody (Minibody) Human Minibody BAFF Mouse IL17 Mouse Inquiry
MiniB-018 Recombinant Anti-BAFF x Anti-B7RP1 Bispecific Antibody (Minibody) Human Minibody BAFF Mouse B7RP1 Mouse Inquiry
SCDB-H197 Recombinant Human Anti-BAFF x Anti-IL17 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody BAFF Human IL17 Human Inquiry
SCDB-H196 Recombinant Human Anti-BAFF x Anti-B7RP1 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody BAFF Human B7RP1 Human Inquiry
FABIG-H197 Recombinant Human Anti-BAFF x Anti-IL17 Bispecific Antibody (Fab-IgG) Human Fab-IgG BAFF Human IL17 Human Inquiry
FABIG-H196 Recombinant Human Anti-BAFF x Anti-B7RP1 Bispecific Antibody (Fab-IgG) Human Fab-IgG BAFF Human B7RP1 Human Inquiry
TRIB-H199 Recombinant Human Anti-BAFF x Anti-IL17 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv BAFF Human IL17 Human Inquiry
TRIB-H198 Recombinant Human Anti-BAFF x Anti-B7RP1 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv BAFF Human B7RP1 Human Inquiry
BSIG-H197 Human Anti-BAFF x Anti-IL17 Bispecific Antibody (IgG-IgG) Human IgG-IgG BAFF Human IL17 Human Inquiry
BSIG-H196 Human Anti-BAFF x Anti-B7RP1 Bispecific Antibody (IgG-IgG) Human IgG-IgG BAFF Human B7RP1 Human Inquiry
CROSSAB-H197 Recombinant Human Anti-BAFF x Anti-IL17 Bispecific Antibody (CrossMab) Human CrossMab BAFF Human IL17 Human Inquiry
CROSSAB-H196 Recombinant Human Anti-BAFF x Anti-B7RP1 Bispecific Antibody (CrossMab) Human CrossMab BAFF Human B7RP1 Human Inquiry
IGFV-H197 Recombinant Human Anti-BAFF x Anti-IL17 Bispecific Antibody (IgG-scFv) Human IgG-scFv BAFF Human IL17 Human Inquiry
IGFV-H196 Recombinant Human Anti-BAFF x Anti-B7RP1 Bispecific Antibody (IgG-scFv) Human IgG-scFv BAFF Human B7RP1 Human Inquiry
BSDB-H197 Recombinant Human Anti-BAFF x Anti-IL17 Bispecific Antibody (Diabody) Human Diabody BAFF Human IL17 Human Inquiry
BSDB-H196 Recombinant Human Anti-BAFF x Anti-B7RP1 Bispecific Antibody (Diabody) Human Diabody BAFF Human B7RP1 Human Inquiry
BSFAB-H197 Recombinant Human Anti-BAFF x Anti-IL17 Bispecific Antibody (Tandem Fab) Human Tandem Fab BAFF Human IL17 Human Inquiry
BSFAB-H196 Recombinant Human Anti-BAFF x Anti-B7RP1 Bispecific Antibody (Tandem Fab) Human Tandem Fab BAFF Human B7RP1 Human Inquiry
BSFV-H197 Recombinant Human Anti-BAFF x Anti-IL17 Bispecific Antibody (Tandem scFv) Human Tandem scFv BAFF Human IL17 Human Inquiry
BSFV-H196 Recombinant Human Anti-BAFF x Anti-B7RP1 Bispecific Antibody (Tandem scFv) Human Tandem scFv BAFF Human B7RP1 Human Inquiry
SCDB-019 Recombinant Anti-BAFF x Anti-IL17 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody BAFF Mouse IL17 Mouse Inquiry
SCDB-018 Recombinant Anti-BAFF x Anti-B7RP1 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody BAFF Mouse B7RP1 Mouse Inquiry
FABIG-019 Recombinant Anti-BAFF x Anti-IL17 Bispecific Antibody (Fab-IgG) Human Fab-IgG BAFF Mouse IL17 Mouse Inquiry
FABIG-018 Recombinant Anti-BAFF x Anti-B7RP1 Bispecific Antibody (Fab-IgG) Human Fab-IgG BAFF Mouse B7RP1 Mouse Inquiry
TRIB-019 Recombinant Anti-BAFF x Anti-IL17 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv BAFF Mouse IL17 Mouse Inquiry
TRIB-018 Recombinant Anti-BAFF x Anti-B7RP1 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv BAFF Mouse B7RP1 Mouse Inquiry
BSIG-019 Anti-BAFF x Anti-IL17 Bispecific Antibody (IgG-IgG) Human IgG-IgG BAFF Mouse IL17 Mouse Inquiry
BSIG-018 Anti-BAFF x Anti-B7RP1 Bispecific Antibody (IgG-IgG) Human IgG-IgG BAFF Mouse B7RP1 Mouse Inquiry
CROSSAB-019 Recombinant Anti-BAFF x Anti-IL17 Bispecific Antibody (CrossMab) Human CrossMab BAFF Mouse IL17 Mouse Inquiry
CROSSAB-018 Recombinant Anti-BAFF x Anti-B7RP1 Bispecific Antibody (CrossMab) Human CrossMab BAFF Mouse B7RP1 Mouse Inquiry
IGFV-019 Recombinant Anti-BAFF x Anti-IL17 Bispecific Antibody (IgG-scFv) Human IgG-scFv BAFF Mouse IL17 Mouse Inquiry
IGFV-018 Recombinant Anti-BAFF x Anti-B7RP1 Bispecific Antibody (IgG-scFv) Human IgG-scFv BAFF Mouse B7RP1 Mouse Inquiry
BSDB-019 Recombinant Anti-BAFF x Anti-IL17 Bispecific Antibody (Diabody) Human Diabody BAFF Mouse IL17 Mouse Inquiry
BSDB-018 Recombinant Anti-BAFF x Anti-B7RP1 Bispecific Antibody (Diabody) Human Diabody BAFF Mouse B7RP1 Mouse Inquiry
BSFAB-019 Recombinant Anti-BAFF x Anti-IL17 Bispecific Antibody (Tandem Fab) Human Tandem Fab BAFF Mouse IL17 Mouse Inquiry
BSFAB-018 Recombinant Anti-BAFF x Anti-B7RP1 Bispecific Antibody (Tandem Fab) Human Tandem Fab BAFF Mouse B7RP1 Mouse Inquiry
BSFV-019 Recombinant Anti-BAFF x Anti-IL17 Bispecific Antibody (Tandem scFv) Human Tandem scFv BAFF Mouse IL17 Mouse Inquiry
BSFV-018 Recombinant Anti-BAFF x Anti-B7RP1 Bispecific Antibody (Tandem scFv) Human Tandem scFv BAFF Mouse B7RP1 Mouse Inquiry

Background

BAFF, B cell activating factor, stands as a seminal pro-survival cytokine of B cells, its conveyed pro-survival signals have become a pivotal regulator for the survival of memory B cells, autoimmune B cells, and malignant cells in chronic lymphocytic leukemia.

The binding receptors for BAFF encompass BAFFR, TACI, or BCMA. The interaction of BAFF and BAFFR can activate either the classic or non-classic NF-κB signaling pathway, subsequently governing myriad basal survival functions of B cells, inclusive of protein synthesis and energy metabolism. The engagement of BAFF with TACI can trigger the class-switch recombination of immunoglobulins, and, moreover, TACI can also function as a decoy receptor. Distinct from BAFFR and TACI, BCMA exhibits a more pronounced expression level in activated B cells and is constitutively expressed in long-lived plasma cells. The activation of BAFF can enhance the survival of malignant cells in chronic lymphocytic leukemia. Additionally, research has affirmed the prime role that BAFF plays in B cell-related autoimmune diseases or cancers.

BAFF and BAFFR signaling. (Scheweighoffer, et al., 2021) Fig.1 BAFF and BAFFR signaling.1

Reference

  1. Schweighoffer, Tybulewicz, et al. " BAFF signaling in health and disease." Current Opinion in Immunology. 71 (2021): 124-131.
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