Anti-B2M Aptamer(Cat#: CTApt-702)

This product is an aptamer which binds to the B2M with an affinity of <50 nM.

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Specifications
Target Category Protein
Target B2M
Alternative Names Beta-2-Microglobulin; Beta Chain Of MHC Class I Molecules; Beta-2-Microglobin; IMD43; B2M
Gene ID 567
UniProt ID P61769
Target Overview This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.
Chemical Modification DNA
Length 20-40 nt
Affinity (Kd) <50 nM
Binding Conditions/Buffer 10 mM Tris-HCl, pH 8.5
GC Content 38
Molecular Weight 12035.9
Extinction Coefficient 382400
nmoles/OD260 2.343

Customer Review

Top-quality product
Excellent
I've switched from other similar products to this Aptamer as it comes at a relatively lower price without compromising the quality. Fast shipping and excellent customer service, the Anti-B2M worked excellent for my ongoing research.
Have a high binding affinity
Excellent
This aptamer product has good specificity towards B2 microglobulin which helped reduce our false-positive results significantly. The aptamers have a high binding affinity which remarkably improved my assay sensitivity.
Superior quality and good specificity
Excellent
I used this product for my experiment and got highly satisfactory results. Expected compatibility with my sample type and good results even with low sample input.
Affordable, good quality, and stable anti-B2M aptamer
Excellent
Good instructions provided with the shipment, the product worked as expected. Enhanced my immunoprecipitation experiments significantly. Will buy again.
Kudos to the developers of this aptamer
Excellent
The product literature and additional support helped me a lot in understanding its mechanism of action and implementation in my experiments. I appreciate the thorough technical support that comes with this product. It's fantastic for a beginner scientist like me.
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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