This product is an aptamer which binds to the B2M with an affinity of <50 nM.
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| Target Category | Protein |
| Target | B2M |
| Alternative Names | Beta-2-Microglobulin; Beta Chain Of MHC Class I Molecules; Beta-2-Microglobin; IMD43; B2M |
| Gene ID | 567 |
| UniProt ID | P61769 |
| Target Overview | This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia. |
| Chemical Modification | DNA |
| Length | 20-40 nt |
| Affinity (Kd) | <50 nM |
| Binding Conditions/Buffer | 10 mM Tris-HCl, pH 8.5 |
| GC Content | 38 |
| Molecular Weight | 12035.9 |
| Extinction Coefficient | 382400 |
| nmoles/OD260 | 2.343 |
Top-quality productExcellentI've switched from other similar products to this Aptamer as it comes at a relatively lower price without compromising the quality. Fast shipping and excellent customer service, the Anti-B2M worked excellent for my ongoing research.
Have a high binding affinityExcellentThis aptamer product has good specificity towards B2 microglobulin which helped reduce our false-positive results significantly. The aptamers have a high binding affinity which remarkably improved my assay sensitivity.
Superior quality and good specificityExcellentI used this product for my experiment and got highly satisfactory results. Expected compatibility with my sample type and good results even with low sample input.
Affordable, good quality, and stable anti-B2M aptamerExcellentGood instructions provided with the shipment, the product worked as expected. Enhanced my immunoprecipitation experiments significantly. Will buy again.
Kudos to the developers of this aptamerExcellentThe product literature and additional support helped me a lot in understanding its mechanism of action and implementation in my experiments. I appreciate the thorough technical support that comes with this product. It's fantastic for a beginner scientist like me.