Anti-cAMP Aptamer(Cat#: CTMM-0422-MM2)

This product is an aptamer which binds to the cAMP with an affinity of <10 µM.

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5’ Modification
 
3’ Modification
 
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Specifications
Target Category Small Organic
Target cAMP
Alternative Names Cyclic adenosine monophosphate; cyclic AMP
Target Overview Cyclic adenosine monophosphate (cAMP, cyclic AMP, or 3',5'-cyclic adenosine monophosphate) is a second messenger important in many biological processes. cAMP is a derivative of adenosine triphosphate (ATP) and used for intracellular signal transduction in many different organisms, conveying the cAMP-dependent pathway. It should not be confused with 5'-AMP-activated protein kinase (AMP-activated protein kinase).
Chemical Modification RNA
Length 20-40 nt
Affinity (Kd) <10 µM
Binding Conditions/Buffer 20 mM Tris-HCl (pH 7.5 at 23 °C), 450 mM NaCl, 100 mM KCl, 10 mM MgCl2, 1 mM MnCl22, and 5 mM CaCl22.
GC Content 0.5161
Molecular Weight 10044.17 g/mole
Extinction Coefficient 316000 L/(mole·cm)
nmoles/OD260 3.16

Customer Review

Superior in terms of performance and ease of use
Excellent
This aptamer is a gem! It effectively binds to cAMP with minimal background noise, allowing for precise measurements even at low concentrations.
Highly recommended for anyone studying cyclic AMP
Excellent
We switched to the anti-cAMP aptamer from traditional antibody-based assays and haven't looked back since. Its sensitivity and reliability have set a new standard in our lab.
It's now our go-to choice
Excellent
The aptamer is a must-have for anyone studying GPCR signaling pathways. It's robust and reproducible, providing consistent results across different experimental conditions.
A crucial tool in our research toolkit
Excellent
We integrated this aptamer into our biosensor development project and were amazed by its performance. It's highly sensitive and ideal for real-time monitoring applications.
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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