This product is an aptamer which binds to the CD117 (c-kit) with an affinity of <20 nM.
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| Target Category | Protein |
| Target | CD117 (c-kit) |
| Chemical Modification | DNA |
| Length | 20-40 nt |
| Affinity (Kd) | <20 nM |
| Binding Conditions/Buffer | Dulbecco's phosphate-buffered saline with calcium and magnesium (DPBS; Invitrogen) plus 5 mM MgCl2, 0.45% glucose and 100 mg/ml tRNA. |
| GC Content | 0.6552 |
| Molecular Weight | 8839.75 g/mole |
| Extinction Coefficient | 262400 L/(mole·cm) |
| nmoles/OD260 | 3.81 |
This aptamer exceeded my expectationsExcellentWe tested this aptamer for cell imaging, and the results were phenomenal. The aptamer's performance in visualizing CD117 expression was exceptional, providing clarity and accuracy in our studies.
Saved us both time and resourcesExcellentWe used this aptamer for isolating CD117-expressing cells, and the efficiency was impressive. It streamlined our cell sorting process, reducing time and improving the purity of the isolated cells.
A critical tool in our investigationExcellentThis aptamer was easy to work with and provided consistent results in our binding studies. Its versatility and stability in various experimental conditions were a significant advantage.
A reliable tool in our researchExcellentThe aptamer provided excellent results in our flow cytometry experiments. The clear and distinct separation of cell populations was notable, and it significantly reduced background noise.
Particularly useful in our workflowsExcellentUsing the CD117 aptamer has streamlined our immunoprecipitation procedures. Its strong and specific binding to the c-kit receptor has reduced our need for additional purification steps, saving us both time and resources.