BCX 1470(Cat#: CTI-015)
This product is a potent and selective factor D antagonist, it inhibits factor D with the IC50 of 96 nM. It also inhibits C1s with the IC50 of 1.6 nM.
Summary
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Specifications
| CAS No. |
217099-43-9 |
| Formula |
C₁₄H₁₀N₂O₂S₂ |
| Molecular Weight |
302.37 |
| SMILES |
N=C(C1=CC2=CC=C(OC(C3=CC=CS3)=O)C=C2S1)N |
| IC50 |
IC50: 96 nM (Factor D); 1.6 nM (C1s); 326 nM (Trypsin) |
| Purity |
95% |
| Storage |
Store at -4°C for short term; at -20 °C for long-term storage. |
| Target |
Factor D |
| Introduction |
The Factor D is a member of the trypsin family of peptidases. It is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. This protein is also a serine protease that is secreted by adipocytes into the bloodstream. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
