FD-IN-1(Cat#: CTI-009)
This product is a potent factor D antagonist, it inhibits factor D with the IC50 of 12 nM. It also inhibits factor XIa (FXIa) and Tryptase β2 with IC50s of 7.7 and 6.5µM, respectively.
Summary
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Specifications
| CAS No. |
1646682-14-5 |
| Formula |
C₂₃H₂₃NO₄ |
| Molecular Weight |
377.43 |
| SMILES |
O=C(O)CC1=CC=CC=C1OCC2=CC=CC(C3=CC([C@H](N)CO)=CC=C3)=C2 |
| IC50 |
IC50: 12 nM |
| Purity |
95% |
| Solubility |
Soluble in DMSO |
| Storage |
Store at -4°C for short term; at -20 °C for long-term storage. |
| Target |
Factor D |
| Introduction |
The Factor D is a member of the trypsin family of peptidases. It is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. This protein is also a serine protease that is secreted by adipocytes into the bloodstream. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
