This product is an Anti-Human rC5a Polyclonal Antiserum from rabbits immunized with highly purified human rabbits protein. It is not a purified IgG fraction.
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| Host Animal | Rabbits |
| Isotype | IgG |
| Immunogen | rC5a protein |
| Applications | Western Blots; ELISA; Immunodiffusion |
| Application Notes | Immunodiffusion: 1/4; WB: 1/500 to 1/1000; ELISA: 1/500 to 1/2000 |
| Specificity | rC5a |
| Format | Frozen liquid |
| Size | 1ml |
| Storage | Store at 4°C short term. Store at -20°C or below long term. Avoid freeze-thaw cycles. |
| Target Name | C5a |
| Alternative Names | Complement C5a; C5a fragment; C5a anaphylatoxin |
| Gene ID | 727 |
| UniProt ID | P01031 |
| Introduction | Complement C5a, together with C5b, are protein fragments released from cleavage of complement component C5 by protease C5-convertase. C5a is a chemotactic agent, as well as an anaphylatoxin, playing critical roles in migration and adherence of neutrophils and monocytes, smooth muscle contraction, and vascular permeability increase. |