Goat Complement Factor B ELISA Kit(Cat#: CTK-461)

This product is an ELISA kit for the determination of Goat Complement Factor B in the samples of Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate. It is highly sensitive and available for the detection of Goat Complement Factor B as low as 0.04 ng/mL.

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Specifications
Assay Type Sandwich ELISA
Sensitivity 0.04 ng/mL (0.156-10 ng/mL)
Pack Size 96 tests
Species Reactivity Goat
Target Factor B
Cross Reactivity No significant cross-reactions have been observed between Goat Complement Factor B and analogues, but existing techniques may limit the detection of cross-reactions with untested analogues.
Applications ELISA
Storage The storage of components varies. Please refer to the instructions for details.
Information
Introduction Complement factor B is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes. It also involves in cleavage of Arg-|-Ser bond in complement component C3 alpha-chain to yield C3a and C3b, and Arg-|-Xaa bond in complement component C5 alpha-chain to yield C5a and C5b.
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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