Dog Complement Factor B ELISA Kit(Cat#: CTK-462)
This product is an ELISA kit for the determination of Dog Complement Factor B in the samples of Cell Culture Supernatant, Plasma, Serum, Tissue Homogenate. It is highly sensitive and available for the detection of Dog Complement Factor B as low as 1.0 pg/mL.
Summary
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Specifications
| Assay Type |
Competition ELISA |
| Sensitivity |
1.0 pg/mL (100-2500 pg/mL) |
| Pack Size |
96 tests |
| Species Reactivity |
Canine |
| Target |
Factor B |
| Applications |
ELISA |
| Storage |
4°C |
Information
| Introduction |
Complement factor B is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes. It also involves in cleavage of Arg-|-Ser bond in complement component C3 alpha-chain to yield C3a and C3b, and Arg-|-Xaa bond in complement component C5 alpha-chain to yield C5a and C5b. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
