Monkey Complement C5a ELISA Kit(Cat#: CTK-331)
This product is an ELISA kit for the determination of Monkey Complement C5a in the samples of Plasma, Serum and Tissue Homogenates. It is highly sensitive and available for the detection of Monkey Complement C5a as low as 0.094 ng/mL.
Summary
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Specifications
| Assay Type |
Sandwich ELISA |
| Sensitivity |
0.094 ng/mL (0.156-10 ng/mL) |
| Pack Size |
96 tests |
| Species Reactivity |
Monkey |
| Target |
C5a |
| Cross Reactivity |
No significant cross-reactions have been observed between Monkey Complement C5a and analogues, but existing techniques may limit the detection of cross-reactions with untested analogues. |
| Applications |
ELISA |
| Storage |
4°C |
Information
| Introduction |
Complement C5a is the alpha chain released from cleavage of complement C5 protein, which plays an important role in chemotaxis. C5a is an effective chemoattractant, initiating accumulation of complement and phagocytic cells at sites of infection or recruitment of antigen-presenting cells to lymph nodes. C5a plays a key role in increasing migration and adherence of neutrophils and monocytes to vessel walls. White blood cells are activated by upregulation of integrin avidity, the lipoxygenase pathway and arachidonic acid metabolism. C5a also modulates the balance between activating versus inhibitory IgG Fc receptors on leukocytes, thereby enhancing the autoimmune response. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
