This product is an unconjugated anti-Human Complement C5a Monoclonal antibody (CTJS-618) generated from the Mouse. The antibody can be used for WB; ELISA; Neut.
Clonality | Monoclonal |
Clone | CTJS-618 |
Host Animal | Mouse |
Isotype | IgG1 |
Immunogen | E. coli-derived recombinant human Complement Component C5a Thr678-Arg751 |
Species Reactivity | Human |
Applications | WB; ELISA; Neut |
Application Notes | WB: 1 µg/mL Neutralization: 0.04-0.12 µg/mL The optimal working dilutions should be determined by the end user. |
Specificity | This antibody reacts with Human complement C5/C5a. |
Purity | ≥95% as determined by SDS-PAGE |
Format | Lyophilized |
Size | 25; 100; 500 µg |
Storage | 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
Type | Primary Antibody |
ProAb | NeutAb |
Target Name | C5a |
Alternative Names | Complement C5a; C5a fragment; C5a anaphylatoxin |
Gene ID | 727 |
UniProt ID | P01031 |
Introduction | Complement C5a, together with C5b, are protein fragments released from cleavage of complement component C5 by protease C5-convertase. C5a is a chemotactic agent, as well as an anaphylatoxin, playing critical roles in migration and adherence of neutrophils and monocytes, smooth muscle contraction, and vascular permeability increase. |