Mouse Anti-Human Complement C5aR1 Monoclonal Antibody (CTJS-31)(Cat#: CTA-1102)
This product is a human complement C5aR1 antibody generated from the Mouse hybridoma. This antibody is available for FC Cytometry, Neutralization.
Summary
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Specifications
| Clonality |
Monoclonal |
| Clone |
CTJS-31 |
| Host Animal |
Mouse |
| Isotype |
IgG2a |
| Immunogen |
Recombinant human C5a R1, a.a. 1-350 |
| Species Reactivity |
Human |
| Applications |
FC; Neut |
| Application Notes |
The optimal working dilutions should be determined by the end user. |
| Specificity |
This antibody reacts with Human C5aR1. |
| Purity |
≥95% as determined by SDS-PAGE |
| Conjugation |
Unconjugated |
| Format |
Lyophilized |
| Size |
100 µg |
| Storage |
Store at 4°C for short term. Store at -20°C for long term. Avoid freeze-thaw cycle. |
| Type |
Primary Antibody |
| ProAb |
NeutAb |
Target
| Target Name |
C5aR1 |
| Alternative Names |
Complement C5a Receptor 1; C5AR; C5a Anaphylatoxin Chemotactic Receptor 1; Complement Component 5a Receptor 1; C5a-R; C5R1; CD88; Complement Component 5 Receptor 1 (C5a Ligand); C5a Anaphylatoxin Chemotactic Receptor 4; Complement Component 5 Receptor 1; C5a Anaphylatoxin Receptor; CD88 Antigen; C5AR1; C5aR |
| Gene ID |
728 |
| UniProt ID |
P21730 |
Information
| Introduction |
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
