Native Human Complement Factor B Protein(Cat#: CTP-294)
This product is a 93 kDa native human Factor B protein isolated from normal human serum. It is availible for Functional Assays, ELISA.
Summary
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Specifications
| Specie Reactivity |
Human |
| Target |
Factor B |
| Molecule Mass |
93 kDa |
| Purity |
>95% determined by SDS-PAGE |
| Endotoxin |
<1.0EU per 1µg (determined by the LAL method) |
| Formulation |
10 mM sodium phosphate, 145 mM NaCl, pH 7.2 |
| Applications |
Functional Assays; ELISA |
| Product Form |
Frozen liquid |
| Storage |
Store at -20°C/-80°C. Avoid freeze-thaw cycles. |
Protein Information
| Introduction |
Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes. |
| Alternative Names |
Complement Factor B; B-Factor, Properdin; Properdin Factor B; Glycine-Rich Beta-Glycoprotein; Glycine-Rich Beta Glycoprotein; C3 Proaccelerator; C3 Proactivator; CFB; FB |
| Gene ID |
629 |
| UniProt ID |
P00751 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
