This product is a ~1,030 kDa native human SC5b-9 Complex protein isolated from normal human serum. It is availible for ELISA.
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| Specie Reactivity | Human |
| Target | C5b-9 Complex |
| Molecule Mass | ~1,030 kDa |
| Purity | >90 % determined by SDS-PAGE |
| Endotoxin | <1.0EU per 1µg (determined by the LAL method) |
| Formulation | 10 mM Sodium phosphate, 145 mM NaCl, pH 7.3 |
| Applications | ELISA |
| Product Form | Frozen liquid |
| Storage | Store at -20°C/-80°C. Avoid freeze-thaw cycles. |
| Introduction | C5b-9 complex is composed of the complement components C5b, C6, C7, C8 and several C9 molecules. It is a complex of proteins typically formed on the surface of pathogen cell membranes as a result of the activation of the host's complement system, and as such is an effector of the immune system. Assembly of the MAC leads to pores that disrupt the cell membrane of target cells, leading to cell lysis and death. |
| Alternative Names | Membrane attack complex; MAC; Terminal complement complex; TCC; scC5b-9 |
It has made our experiments much more efficientExcellentAs a researcher, I appreciate the consistent performance of the native human complement SC5b-9 complex protein. It's easy to use, and the detailed protocol provided ensures that even new lab members can handle it effectively.
The quality of this complement protein is outstandingExcellentOur lab switched to this product after experiencing variability with other suppliers. The protein has exceeded our expectations in terms of consistency and reliability. It has helped us achieve clearer and more definitive results in our immunology studies, particularly in quantifying complement activation.
The SC5b-9 complex is vital for our studiesExcellentThis protein has become an essential part of our ELISA assays. The high purity and specific activity levels ensure that our experimental outcomes are both accurate and reproducible, saving us time and resources.
Reliable and easy to work withExcellentUsing the protein has been a pleasure. The documentation and support provided are excellent, making it straightforward to integrate into our existing protocols and achieve high-quality results.