Rabbit Anti-Human Vitronectin Polyclonal Antiserum(Cat#: CTA-P-022)

Name: Rabbit Anti-Human Vitronectin Polyclonal Antiserum
SKU: CTA-P-022
Rating: 5 (1 reviews)

This product is an Anti-Human Vitronectin Polyclonal Antiserum from rabbits immunized with highly purified human Vitronectin protein. It is not a purified IgG fraction.

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Specifications

Host Animal	Rabbits
Isotype	IgG
Immunogen	Vitronectin protein
Applications	Western Blots; ELISA; Immunodiffusion
Application Notes	Immunodiffusion: 1/8; WB: 1/500 to 1/1000; ELISA: 1/500 to 1/2000
Specificity	Vitronectin
Format	Frozen liquid
Size	1ml
Storage	Store at 4°C short term. Store at -20°C or below long term. Avoid freeze-thaw cycles.

Target

Target Name	Vitronectin
Alternative Names	Serum Spreading Factor; Complement S-Protein; Somatomedin B; S-Protein; V75; VN; Vitronectin (Serum Spreading Factor, Somatomedin B, Complement S-Protein); Serum-Spreading Factor; Epibolin; VNT
Gene ID	7448
UniProt ID	P04004

Information

Introduction

Vitronectin (VTN or VN) is a glycoprotein of the hemopexin family which is abundantly found in serum, the extracellular matrix and bone.In humans it is encoded by the VTN gene. Vitronectin binds to integrin alpha-V beta-3 and thus promotes cell adhesion and spreading. It also inhibits the membrane-damaging effect of the terminal cytolytic complement pathway and binds to several serpins (serine protease inhibitors). It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond. Vitronectin has been speculated to be involved in hemostasis and tumor malignancy.

For Research Use Only. Not for Diagnostic or Therapeutic Applications.