Recombinant Human Complement Component C5a R1 Protein(Cat#: CTP-084)

Name: Recombinant Human Complement Component C5a R1 Protein
SKU: CTP-084
Rating: 5 (1 reviews)

This product is a 39.3 Kda recombinant human Complement Component C5a R1 protein expressed in the E. coli. It is available for Bioactivity Assays.

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Specifications

Expressed Host	E. Coli
Specie Reactivity	Human
Target	C5aR1
Molecule Mass	39.3 KDa
Purity	>95% by SDS-PAGE
Endotoxin	<1.0EU per 1µg (determined by the LAL method)
Formulation	Lyophilized with no additives. (Reconstitute to 1.0 mg/ml in ice-cold H2O containing 2.5 mg/ml BSA. The solution should be aliquoted and immediately stored at -70C for long-term storage. Frozen/thaw will result in some loss of activity.)
Applications	Bioactivity Assays
Product Form	Lyophilized
Storage	Store at 2 to 8°C after reconstitution for short term (1-2 weeks). For long term storage, aliquot and store at -20 or -80°C. Avoid repeated freezing and thawing cycles.

Protein Information

Introduction	C5a anaphylatoxin chemotactic receptor 1 is the receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production.
Alternative Names	C5a anaphylatoxin chemotactic receptor; C5A; C5aR; C5a-R; C5AR1; C5ARC5a anaphylatoxin receptor; C5R1C5a ligand; CD88 antigen; CD88; complement component 5 receptor 1 (C5a ligand); complement component 5 receptor 1; complement component 5a receptor 1; Complement Component C5a R1; Complement Component C5aR1
Gene ID	728
UniProt ID	P21730

For Research Use Only. Not for Diagnostic or Therapeutic Applications.