Recombinant Human Complement Component C5a R1 Protein(Cat#: CTP-084)
This product is a 39.3 Kda recombinant human Complement Component C5a R1 protein expressed in the E. coli. It is available for Bioactivity Assays.
Summary
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Specifications
| Expressed Host |
E. Coli |
| Specie Reactivity |
Human |
| Target |
C5aR1 |
| Molecule Mass |
39.3 KDa |
| Purity |
>95% by SDS-PAGE |
| Endotoxin |
<1.0EU per 1µg (determined by the LAL method) |
| Formulation |
Lyophilized with no additives. (Reconstitute to 1.0 mg/ml in ice-cold H2O containing 2.5 mg/ml BSA. The solution should be aliquoted and immediately stored at -70C for long-term storage. Frozen/thaw will result in some loss of activity.) |
| Applications |
Bioactivity Assays |
| Product Form |
Lyophilized |
| Storage |
Store at 2 to 8°C after reconstitution for short term (1-2 weeks). For long term storage, aliquot and store at -20 or -80°C. Avoid repeated freezing and thawing cycles. |
Protein Information
| Introduction |
C5a anaphylatoxin chemotactic receptor 1 is the receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production. |
| Alternative Names |
C5a anaphylatoxin chemotactic receptor; C5A; C5aR; C5a-R; C5AR1; C5ARC5a anaphylatoxin receptor; C5R1C5a ligand; CD88 antigen; CD88; complement component 5 receptor 1 (C5a ligand); complement component 5 receptor 1; complement component 5a receptor 1; Complement Component C5a R1; Complement Component C5aR1 |
| Gene ID |
728 |
| UniProt ID |
P21730 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
