Recombinant Anti-CCR3 x Anti-CD300 Bispecific Antibody (scFv-Fc)  (BSCFV-028)

Recombinant Anti-CCR3 x Anti-CD300 Bispecific Antibody (scFv-Fc) is formed by fusing two different scFv fragments to the hinge and Fc regions, in which the Fc region are engineered by KIH. Two of scFv moiety has the antibody variable domain of either anti-CCR3 specificity or anti-CD300 specificity, which produces bivalent IgG-like molecules with desired characteristics of intact antibodies. This BsAb canreduce eosinophil signaling, inhibit bronchoalveolar lavage fluid inflammation, eosinophil, mast cell mediator release and reverse lung inflammation. It is designed for the research of Asthma therapy.

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