This product is an aptamer which binds to the ITGAV with a high affinity.
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| Target Category | Protein |
| Target | ITGAV |
| Alternative Names | Integrin Subunit Alpha V;CD51;MSK8;VNRA;VTNR;Integrin, Alpha V (Vitronectin Receptor, Alpha Polypeptide, Antigen CD51) ;Antigen Identified By Monoclonal Antibody L230;Vitronectin Receptor Subunit Alpha;Vitronectin Receptor;Integrin Alpha-V;Integrin AlphaVbeta3;Integrin, Alpha V;CD51 Antigen |
| Gene ID | 3685 |
| UniProt ID | P06756 |
| Target Overview | https://www.genecards.org/cgi-bin/carddisp.pl?gene=ITGAV&keywords=Alpha-V,Beta-3 |
| Chemical Modification | RNA |
| Length | 20-40 nt |
| Affinity (Kd) | N/A |
| Binding Conditions/Buffer | Washed with PBS and 0.9 mM CaCl2, 0.5 mM MgCl2, 2.67 mM KCl, 1.47 mM KH2PO4, 135 mM NaCl, and 8 mM Na2. |
| GC Content | 0.5135 |
| Molecular Weight | 11855.18 g/mole |
| Extinction Coefficient | 364200 L/(mole·cm) |
| nmoles/OD260 | 2.75 |
This product has certainly streamlined our workflowExcellentThe aptamer's performance in our tumor metastasis studies has been outstanding. It binds effectively without causing non-specific interactions, which is crucial for our high-throughput assays.
Highly recommend this for any similar experimental needsExcellentThe aptamer's specificity and low off-target binding have been crucial for our cell adhesion assays. It has allowed us to obtain precise data, contributing to our understanding of endothelial cell interactions.
Precise and reliable resultsExcellentIt has allowed us to obtain high-quality data with minimal background interference. This product has undoubtedly enhanced the efficiency of our experiments.