Anti-Endothelial Integrin Alpha-V Beta-3 Aptamer(Cat#: CTApt-M-1891)

This product is an aptamer which binds to the ITGAV with a high affinity.

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5’ Modification
 
3’ Modification
 
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Specifications
Target Category Protein
Target ITGAV
Alternative Names Integrin Subunit Alpha V;CD51;MSK8;VNRA;VTNR;Integrin, Alpha V (Vitronectin Receptor, Alpha Polypeptide, Antigen CD51) ;Antigen Identified By Monoclonal Antibody L230;Vitronectin Receptor Subunit Alpha;Vitronectin Receptor;Integrin Alpha-V;Integrin AlphaVbeta3;Integrin, Alpha V;CD51 Antigen
Gene ID 3685
UniProt ID P06756
Target Overview https://www.genecards.org/cgi-bin/carddisp.pl?gene=ITGAV&keywords=Alpha-V,Beta-3
Chemical Modification RNA
Length 20-40 nt
Affinity (Kd) N/A
Binding Conditions/Buffer Washed with PBS and 0.9 mM CaCl2, 0.5 mM MgCl2, 2.67 mM KCl, 1.47 mM KH2PO4, 135 mM NaCl, and 8 mM Na2.
GC Content 0.5135
Molecular Weight 11855.18 g/mole
Extinction Coefficient 364200 L/(mole·cm)
nmoles/OD260 2.75

Customer Review

This product has certainly streamlined our workflow
Excellent
The aptamer's performance in our tumor metastasis studies has been outstanding. It binds effectively without causing non-specific interactions, which is crucial for our high-throughput assays.
Highly recommend this for any similar experimental needs
Excellent
The aptamer's specificity and low off-target binding have been crucial for our cell adhesion assays. It has allowed us to obtain precise data, contributing to our understanding of endothelial cell interactions.
Precise and reliable results
Excellent
It has allowed us to obtain high-quality data with minimal background interference. This product has undoubtedly enhanced the efficiency of our experiments.
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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