Monkey Complement C3 ELISA Kit-CTK-140(Cat#: CTK-140)

This product is an ELISA kit for the determination of Monkey Complement C3 in the samples of Plasma and Serum. It is highly sensitive and available for the detection of Monkey Complement C3 as low as 1.17 ng/mL.

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Specifications
Assay Type Sandwich ELISA
Sensitivity 1.17 ng/mL (4.68-300 ng/mL)
Pack Size 96 tests
Species Reactivity Monkey
Target C3
Cross Reactivity No significant cross-reactions have been observed between Monkey Complement C3 and analogues, but existing techniques may limit the detection of cross-reactions with untested analogues.
Applications ELISA
Storage The storage of components varies. Please refer to the instructions for details.
Information
Introduction Complement C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. C3-beta-c: Acts as a chemoattractant for neutrophils in chronic inflammation. Acylation stimulating protein: adipogenic hormone that stimulates triglyceride (TG) synthesis and glucose transport in adipocytes, regulating fat storage and playing a role in postprandial TG clearance. Appears to stimulate TG synthesis via activation of the PLC, MAPK and AKT signaling pathways. Ligand for C5AR2. Promotes the phosphorylation, ARRB2-mediated internalization and recycling of C5AR2.

Customer Review

Using the kit was a breeze
Excellent
This kit is a must-have for researchers investigating complement pathways in primate models. Customer support was also excellent, providing prompt assistance when needed.
Our lab relies heavily on the accuracy of ELISA kits
Excellent
It performed reliably, delivering precise measurements of C3 concentrations in monkey serum. The data generated were crucial for our comparative immunology study. I appreciate the kit's robust design and ease of use, making it suitable for both experienced researchers and newcomers in the field.
I would highly recommend this kit
Excellent
It enabled us to detect subtle changes in complement activity in our primate samples with high sensitivity. The kit's components were well-packaged, and the assay protocol was user-friendly. It significantly contributed to our understanding of primate immune responses.
I commend this kit for its reliability and ease of use
Excellent
We utilized the kit for our primate research project and were impressed by its performance. The kit's sensitivity and specificity were excellent, enabling accurate quantification of C3 in monkey serum samples. The results were consistent across different experimental conditions, providing robust data for our study on complement activation pathways.
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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