Native Cynomolgus Monkey Complement C3 Protein(Cat#: CTP-506)

Name: Native Cynomolgus Monkey Complement C3 Protein
SKU: CTP-506

This product is a 185 kDa native Cynomolgus Monkey C3 protein isolated from normal Cynomolgus Monkey serum. It is availible for Functional Assays.

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Specifications

Specie Reactivity	Cynomolgus Monkey
Target	C3
Molecule Mass	185 kDa
Purity	>85% determined by SDS-PAGE
Endotoxin	<1.0EU per 1µg (determined by the LAL method)
Formulation	10 mM sodium phosphate, 145 mM NaCl, pH 7.2
Applications	Functional Assays
Product Form	Frozen liquid
Storage	Store at -20°C/-80°C. Avoid freeze-thaw cycles.

Protein Information

Introduction	C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. In chronic inflammation, acts as a chemoattractant for neutrophils (By similarity). It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. [C3-beta-c]: Acts as a chemoattractant for neutrophils in chronic inflammation. [Acylation stimulating protein]: adipogenic hormone that stimulates triglyceride (TG) synthesis and glucose transport in adipocytes, regulating fat storage and playing a role in postprandial TG clearance. Appears to stimulate TG synthesis via activation of the PLC, MAPK and AKT signaling pathways. Ligand for C5AR2. Promotes the phosphorylation, ARRB2-mediated internalization and recycling of C5AR2.
Alternative Names	Complement C3; Complement Component 3; Complement Component C3; C3
Gene ID	102131458
UniProt ID	A0A2K5VPN1

Customer Review

Hands down the best product for my scientific experiment needs

Excellent

The native cynomolgus monkey complement C3 protein has been perfect for our lab's projects! Its consistent quality and reliable performance significantly improved our results. As a scientist, I would highly recommend this protein for precise, critical experiments.

As a long-time customer, I can vouch for the effectiveness of the C3 protein

Excellent

The protein showed high stability and functioned as expected in our tests. We encountered no difficulties or abnormalities. I would recommend the C3 protein to my colleagues.

Its consistent potency and high purity yield excellent results

Excellent

For researchers seeking reliable lab proteins, the protein is a great choice. It has a solid constitution, works great in our experiments, and their customer service is efficient, ensuring prompt delivery for every order.

A well-made product with excellent quality

Excellent

From potency to stability, it scored high in all our assays. For research labs considering this product, I can confidently say that it is worth the investment.

For Research Use Only. Not for Diagnostic or Therapeutic Applications.