Monkey Complement C5 ELISA Kit(Cat#: CTK-316)

Name: Monkey Complement C5 ELISA Kit
SKU: CTK-316

This product is an ELISA kit for the determination of Monkey Complement C5 in the samples of Plasma, Serum and Tissue Homogenates. It is highly sensitive and available for the detection of Monkey Complement C5 as low as 0.156 ng/mL.

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Specifications

Assay Type	Sandwich ELISA
Sensitivity	0.156 ng/mL (0.625-40 ng/mL)
Pack Size	96 tests
Species Reactivity	Monkey
Target	C5
Cross Reactivity	No significant cross-reactions have been observed between Monkey Complement C5 and analogues, but existing techniques may limit the detection of cross-reactions with untested analogues.
Applications	ELISA
Storage	Store at 4°C/-20°C, please refer to the instructions for details.

Information

Introduction

Complement component 5 is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. C5 is composed of alpha (C5a) and beta (C5b) polypeptide chains. Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled. Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process. Binding to the receptor C5AR1 induces a variety of responses including intracellular calcium release, contraction of smooth muscle, increased vascular permeability, and histamine release from mast cells and basophilic leukocytes. C5a is also a potent chemokine which stimulates the locomotion of polymorphonuclear leukocytes and directs their migration toward sites of inflammation.

Customer Review

Easy to use and robust kit

Excellent

The kit was well-packaged and came with everything needed. Instructions were straightforward, and the assay was reproducible. Great for our lab's needs.

Very satisfied

Excellent

Excellent customer support provided by the company. They were quick to address our queries regarding protocol optimization. The kit itself worked flawlessly.

The assay is user-friendly, saving us valuable time

Excellent

Accurate quantification of C5 levels even in complex biological samples. The kit's performance exceeded our expectations, and we plan to continue using it.

A reliable tool for our immunology research

Excellent

Efficient and economical choice for C5 detection in monkeys. The data obtained has been critical for advancing our understanding of primate immunology.

For Research Use Only. Not for Diagnostic or Therapeutic Applications.