This product is a conjugated anti-Human Complement C1 Inhibitor Monoclonal antibody (CTJS-12) generated from the Mouse. The antibody can be used for WB, IF, IHC, FC.
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| Clonality | Monoclonal |
| Clone | CTJS-12 |
| Host Animal | Mouse |
| Isotype | IgG1 κ |
| Immunogen | Recombinant Human C1 Inhibitor, a.a. 215-249 |
| Species Reactivity | Human; Mouse; rat |
| Applications | WB; IF; IHC; FC |
| Application Notes | The optimal working dilutions should be determined by the end user. |
| Specificity | This antibody reacts with Human, Mouse, and Rat Complement C1 Inhibitor. |
| Purity | ≥95% as determined by SDS-PAGE |
| Conjugation | iFluor® 594 |
| Format | Liquid |
| Size | 200 µg |
| Storage | Store in dark at 4°C. Do Not Freeze. |
| Type | Primary Antibody |
| Target Name | C1 Inhibitor |
| Alternative Names | Serpin Family G Member 1; Plasma Protease C1 Inhibitor; C1IN; Serpin Peptidase Inhibitor, Clade G (C1 Inhibitor), Member 1; C1 Esterase Inhibitor; C1-Inhibiting Factor;C1-Inhibitor; C1INH; ; Serine/Cysteine Proteinase Inhibitor Clade G Member 1; Epididymis Secretory Sperm Binding Protein; Complement Component 1 Inhibitor; SERPING1; C1-INH; C1Inh |
| Gene ID | 710 |
| UniProt ID | P05155 |
| Introduction | Activation of the C1 complex is under control of the C1-inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein. |