Mouse Anti-Human CFHR1 Monoclonal Antibody (CTJS-570)(Cat#: CTA-135)
This product is an unconjugated anti-Human CFHR1 Monoclonal antibody (CTJS-570) generated from the Mouse. The antibody can be used for WB; IP.
Summary
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Specifications
| Clonality |
Monoclonal |
| Clone |
CTJS-570 |
| Host Animal |
Mouse |
| Isotype |
IgG2b |
| Immunogen |
Mouse myeloma cell line NS0-derived recombinant human Complement Factor H-related 1/CFHR1
Glu19-Ala328 |
| Species Reactivity |
Human |
| Applications |
WB; IP |
| Application Notes |
WB: 1 µg/mL
IP: 25 µg/mL
The optimal working dilutions should be determined by the end user. |
| Specificity |
This antibody reacts with Human CFHR1. |
| Purity |
≥95% as determined by SDS-PAGE |
| Format |
Lyophilized |
| Size |
25; 100 µg |
| Storage |
12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
| Type |
Primary Antibody |
Target
| Target Name |
CFHR1 |
| Alternative Names |
Complement Factor H-Related 1 Pseudogene; H Factor (Complement)-Like 1; H Factor (Complement)-Like 2; H Factor-Like Protein 1; H-Factor-Like 1; Complement Factor H-Related Protein 1; FHR-1; H36; CFHL; FHR1; HFL1; HFL2; CFHL1; H36-1; H36-2; CFHL1P; CFHR1P |
| Gene ID |
3078 |
| UniProt ID |
Q03591 |
Information
| Introduction |
Complement factor H-related protein 1 is a protein that in humans is encoded by the CFHR1 gene. This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
