Mouse Anti-Human CFHR1 Monoclonal Antibody (CTJS-570)(Cat#: CTA-135)

Name: Mouse Anti-Human CFHR1 Monoclonal Antibody (CTJS-570)
SKU: CTA-135
Rating: 5 (1 reviews)

This product is an unconjugated anti-Human CFHR1 Monoclonal antibody (CTJS-570) generated from the Mouse. The antibody can be used for WB; IP.

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Specifications

Clonality	Monoclonal
Clone	CTJS-570
Host Animal	Mouse
Isotype	IgG2b
Immunogen	Mouse myeloma cell line NS0-derived recombinant human Complement Factor H-related 1/CFHR1 Glu19-Ala328
Species Reactivity	Human
Applications	WB; IP
Application Notes	WB: 1 µg/mL IP: 25 µg/mL The optimal working dilutions should be determined by the end user.
Specificity	This antibody reacts with Human CFHR1.
Purity	≥95% as determined by SDS-PAGE
Format	Lyophilized
Size	25; 100 µg
Storage	12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Type	Primary Antibody

Target

Target Name	CFHR1
Alternative Names	Complement Factor H-Related 1 Pseudogene; H Factor (Complement)-Like 1; H Factor (Complement)-Like 2; H Factor-Like Protein 1; H-Factor-Like 1; Complement Factor H-Related Protein 1; FHR-1; H36; CFHL; FHR1; HFL1; HFL2; CFHL1; H36-1; H36-2; CFHL1P; CFHR1P
Gene ID	3078
UniProt ID	Q03591

Information

Introduction

Complement factor H-related protein 1 is a protein that in humans is encoded by the CFHR1 gene. This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.

For Research Use Only. Not for Diagnostic or Therapeutic Applications.