Anti-17β-Estradiol aptamer(Cat#: CTApt-2054)

This product is an aptamer which binds to the 17β-Estradiol with an affinity of <20 nM.

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5’ Modification
 
3’ Modification
 
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Summary

Specifications
Target Category Small Organic
Target 17β-Estradiol
Target Overview 17beta-estradiol is the 17beta-isomer of estradiol. It has a role as an estrogen, a human metabolite, an EC 1.2.3.1 (aldehyde oxidase) inhibitor, a Daphnia magna metabolite and a mouse metabolite. It is a 17beta-hydroxy steroid and an estradiol.
Chemical Modification DNA
Length 20-40 nt
Affinity (Kd) <20 nM
Binding Conditions/Buffer 2 mM Tris−HCl at pH 7.5 containing 10 mM NaCl, 0.5 mM KCl, 0.2 mM MgCl2, 0.1 mM CaCl2, and 5% ethanol
GC Content 0.57
Molecular Weight 10868.1
nmoles/OD260 2.638
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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