This product is an aptamer which binds to the 17β-Estradiol with an affinity of <20 nM.
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| Target Category | Small Organic |
| Target | 17β-Estradiol |
| Target Overview | 17beta-estradiol is the 17beta-isomer of estradiol. It has a role as an estrogen, a human metabolite, an EC 1.2.3.1 (aldehyde oxidase) inhibitor, a Daphnia magna metabolite and a mouse metabolite. It is a 17beta-hydroxy steroid and an estradiol. |
| Chemical Modification | DNA |
| Length | 20-40 nt |
| Affinity (Kd) | <20 nM |
| Binding Conditions/Buffer | 2 mM Tris−HCl at pH 7.5 containing 10 mM NaCl, 0.5 mM KCl, 0.2 mM MgCl2, 0.1 mM CaCl2, and 5% ethanol |
| GC Content | 0.57 |
| Molecular Weight | 10868.1 |
| nmoles/OD260 | 2.638 |