Anti-AASS Aptamer(Cat#: CTApt-2374)
This product is an aptamer which binds to the AASS with an affinity of 1nM~1μM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
AASS |
| Alternative Names |
Aminoadipate-Semialdehyde Synthase; Alpha-Aminoadipic Semialdehyde Synthase, Mitochondrial; LKR/SDH; LKRSDH; LORSDH; Lysine-Ketoglutarate Reductase /Saccharopine Dehydrogenase; Lysine Ketoglutarate Reductase/Saccharopine Dehydrogenase; Alpha-Aminoadipate Semialdehyde Synthase; Alpha-Aminoadipic Semialdehyde Synthase; Aminoadipic Semialdehyde Synthase; Lysine-2-Oxoglutarate Reductase; AASS |
| Gene ID |
10157 |
| UniProt ID |
Q9UDR5 |
| Target Overview |
This gene encodes a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in this gene are associated with familial hyperlysinemia. |
| Chemical Modification |
DNA/RNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
