Anti-ABCE1 Aptamer(Cat#: CTApt-903)
This product is an aptamer which binds to the ABCE1 with an affinity of 1nM~1μM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
ABCE1 |
| Alternative Names |
ATP Binding Cassette Subfamily E Member 1; RLI; ATP-Binding Cassette, Sub-Family E (OABP), Member 1; ATP-Binding Cassette Sub-Family E Member 1; 2'-5'-Oligoadenylate-Binding Protein; Ribonuclease 4 Inhibitor; RNase L Inhibitor 1; RNASEL1; RNASELI; HuHP68; RNS4I; OABP; RLI1; Ribonuclease L (2',5'-Oligoisoadenylate Synthetase-Dependent) Inhibitor; RNase L Inhibitor; ABC38; ABCE1 |
| Gene ID |
6059 |
| UniProt ID |
P61221 |
| Target Overview |
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene. |
| Chemical Modification |
DNA/RNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
