Anti-ACE2 Aptamer(Cat#: CTApt-945)
This product is an aptamer which binds to the ACE2 with an affinity of 1nM~1μM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
ACE2 |
| Alternative Names |
Angiotensin I Converting Enzyme 2; Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 2; Angiotensin-Converting Enzyme-Related Carboxypeptidase; Angiotensin-Converting Enzyme Homolog; Angiotensin-Converting Enzyme 2; ACE-Related Carboxypeptidase; Metalloprotease MPROT15; Peptidyl-Dipeptidase A; ACEH; EC 3.4.17.23; EC 3.4.17.- ; EC 3.4.17; ACE2 |
| Gene ID |
59272 |
| UniProt ID |
Q9BYF1 |
| Target Overview |
The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronavirus HCoV-NL63 and the human severe acute respiratory syndrome coronaviruses, SARS-CoV and SARS-CoV-2 (COVID-19 virus). |
| Chemical Modification |
DNA/RNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
