This product is an aptamer which binds to the ACOX1 with an affinity of 1nM~1μM.
Target Category | Protein |
Target | ACOX1 |
Alternative Names | Acyl-CoA Oxidase 1; Palmitoyl-CoA Oxidase; Peroxisomal Acyl-Coenzyme A Oxidase 1; Acyl-Coenzyme A Oxidase 1, Palmitoyl; Straight-Chain Acyl-CoA Oxidase; Acyl-CoA Oxidase 1, Palmitoyl; EC 1.3.3.6; PALMCOX; ACOX; SCOX; AOX; Peroxisomal Fatty Acyl-CoA Oxidase; Acyl-CoA Oxidase, Straight-Chain; ACOX1 |
Gene ID | 51 |
UniProt ID | Q15067 |
Target Overview | The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified. |
Chemical Modification | DNA/RNA |
Length | 20-80 nt |
Affinity (Kd) | 1nM~1μM |
Binding Conditions/Buffer | PBS; buffer system with Serum; other |