Anti-ACR Aptamer(Cat#: CTApt-2488)
This product is an aptamer which binds to the ACR with an affinity of 1nM~1μM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
ACR |
| Alternative Names |
Acrosin; Acrosin Light And Heavy Chain Prepropeptide; Preproacrosin; EC 3.4.21.10; Proacrosin; EC 3.4.21; ACRS; ACR |
| Gene ID |
49 |
| UniProt ID |
P10323 |
| Target Overview |
Acrosin is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids. |
| Chemical Modification |
DNA/RNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
