Anti-ADAMTS7 Aptamer(Cat#: CTApt-1254)
This product is an aptamer which binds to the ADAMTS7 with an affinity of 1nM~1μM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
ADAMTS7 |
| Alternative Names |
ADAM Metallopeptidase With Thrombospondin Type 1 Motif 7; ADAM-TS7; COMPase; A Disintegrin-Like And Metalloprotease (Reprolysin Type) With Thrombospondin Type 1 Motif, 7; A Disintegrin And Metalloprotease With Thrombospondin Motifs-7 Preproprotein; A Disintegrin And Metalloproteinase With Thrombospondin Motifs 7; ADAM-TS 7; ADAMTS-7; DKFZp434H204; EC 3.4.24.82; EC 3.4.24.- ; EC 3.4.24; ADAMTS7 |
| Gene ID |
11173 |
| UniProt ID |
Q9UKP4 |
| Target Overview |
The protein encoded by this gene is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and may regulate vascular smooth muscle cell (VSMC) migration. Mutations in this gene may be associated with susceptibility to coronary artery disease. |
| Chemical Modification |
DNA/RNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
