Anti-ADCY6 Aptamer(Cat#: CTApt-2490)
This product is an aptamer which binds to the ADCY6 with an affinity of 1nM~1μM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
ADCY6 |
| Alternative Names |
Adenylate Cyclase 6; Ca(2+)-Inhibitable Adenylyl Cyclase; ATP Pyrophosphate-Lyase 6; Adenylate Cyclase Type VI; Adenylate Cyclase Type 6; EC 4.6.1.1; AC6; Adenylyl Cyclase 6; KIAA042; LCCS8; ADCY6 |
| Gene ID |
112 |
| UniProt ID |
O43306 |
| Target Overview |
This gene encodes a member of the adenylyl cyclase family of proteins, which are required for the synthesis of cyclic AMP. All members of this family have an intracellular N-terminus, a tandem repeat of six transmembrane domains separated by a cytoplasmic loop, and a C-terminal cytoplasmic domain. The two cytoplasmic regions bind ATP and form the catalytic core of the protein. Adenylyl cyclases are important effectors of transmembrane signaling pathways and are regulated by the activity of G protein coupled receptor signaling. This protein belongs to a small subclass of adenylyl cyclase proteins that are functionally related and are inhibited by protein kinase A, calcium ions and nitric oxide. A mutation in this gene is associated with arthrogryposis multiplex congenita. |
| Chemical Modification |
DNA/RNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
