Anti-AGTR1 Aptamer(Cat#: CTApt-1082)
This product is an aptamer which binds to the AGTR1 with an affinity of 1nM~1μM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
AGTR1 |
| Alternative Names |
Angiotensin II Receptor Type 1; AT2R1; AT1; Type-1 Angiotensin II Receptor; AGTR1B; AGTR1A; AT2R1B; AT1AR; AT1BR; HAT1R; AG2S; AT1B; Type-1B Angiotensin II Receptor; Angiotensin II Type-1 Receptor; Angiotensin Receptor 1B; AT2R1A; AGTR1; AT1R |
| Gene ID |
185 |
| UniProt ID |
P30556 |
| Target Overview |
Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene. |
| Chemical Modification |
DNA/RNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
