Anti-AKAP12 Aptamer(Cat#: CTApt-2442)
This product is an aptamer which binds to the AKAP12 with an affinity of 1nM~1μM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
AKAP12 |
| Alternative Names |
A-Kinase Anchoring Protein 12; AKAP250; Src-Suppressed C Kinase Substrate; A Kinase (PRKA) Anchor Protein 12; A-Kinase Anchor Protein 12; AKAP 250; Gravin; SSeCKS; A Kinase (PRKA) Anchor Protein (Gravin) 12; Myasthenia Gravis Autoantigen Gravin; A-Kinase Anchor Protein, 250kDa; A-Kinase Anchor Protein 250 KDa; Kinase Scaffold Protein Gravin; Myasthenia Gravis Autoantigen; AKAP-12; AKAP12 |
| Gene ID |
9590 |
| UniProt ID |
Q02952 |
| Target Overview |
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms. |
| Chemical Modification |
DNA/RNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
