Anti-AKR1C4 Aptamer(Cat#: CTApt-1114)
This product is an aptamer which binds to the AKR1C4 with an affinity of 1nM~1μM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
AKR1C4 |
| Alternative Names |
Aldo-Keto Reductase Family 1 Member C4; HAKRA; CDR; DD4; Chlordecone Reductase; 3-Alpha Hydroxysteroid Dehydrogenase, Type I; Dihydrodiol Dehydrogenase 4; 3-Alpha-HSD1; 3-Alpha-HSD; CHDR; DD-4; C11; Aldo-Keto Reductase Family 1, Member C4 (Chlordecone Reductase; 3-Alpha Hydroxysteroid Dehydrogenase, Type I; Dihydrodiol Dehydrogenase 4) ; Type I 3-Alpha-Hydroxysteroid Dehydrogenase; 3-Alpha-Hydroxysteroid Dehydrogenase Type I; Dihydrodiol Dehydrogenase Isozyme DD4; Dihydrodiol Dehydrogenase 4; Chlordecone Reductase; EC 1.1.1.274; EC 1.1.1.357; EC 1.1.1.225; MGC22581; EC 1.1.1; AKR1C4; |
| Gene ID |
1109 |
| UniProt ID |
P17516 |
| Target Overview |
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. |
| Chemical Modification |
DNA/RNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
