This product is an aptamer which binds to the ALG3 with an affinity of 1nM~1μM.
Target Category | Protein |
Target | ALG3 |
Alternative Names | ALG3 Alpha-1,3- Mannosyltransferase; Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol Alpha-1,3-Mannosyltransferase; NOT56L; Asparagine-Linked Glycosylation 3 Homolog (Yeast, Alpha-1,3-Mannosyltransferase) ; Dolichyl-Phosphate-Mannose--Glycolipid Alpha-Mannosyltransferase; Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-Dolichyl Mannosyltransferase; Carbohydrate Deficient Glycoprotein Syndrome Type IV; Dol-P-Man-Dependent Alpha(1-3)-Mannosyltransferase; Asparagine-Linked Glycosylation Protein 3 Homolog; Not56-Like Protein; D16Ertd36e; CDGS4; Not56; Asparagine-Linked Glycosylation 3, Alpha-1,3- Mannosyltransferase Homolog (S. Cerevisiae) ; Asparagine-Linked Glycosylation 3 Homolog (S. Cerevisiae, Alpha-1,3-Mannosyltransferase) ; Asparagine-Linked Glycosylation 3, Alpha-1,3- Mannosyltransferase Homolog; Dol-P-Man Dependent Alpha-1,3- Mannosyltransferase; EC 2.4.1.130; EC 2.4.1.258; CDG1D; CDGS6; ALG3; Not; NOT |
Gene ID | 10195 |
UniProt ID | Q92685 |
Target Overview | This gene encodes a member of the ALG3 family. The encoded protein catalyses the addition of the first dol-P-Man derived mannose in an alpha 1,3 linkage to Man5GlcNAc2-PP-Dol. Defects in this gene have been associated with congenital disorder of glycosylation type Id (CDG-Id) characterized by abnormal N-glycosylation. Multiple transcript variants encoding different isoforms have been found for this gene. |
Chemical Modification | DNA/RNA |
Length | 20-80 nt |
Affinity (Kd) | 1nM~1μM |
Binding Conditions/Buffer | PBS; buffer system with Serum; other |