Anti-ANAPC2 Aptamer(Cat#: CTApt-1172)
This product is an aptamer which binds to the ANAPC2 with an affinity of 1nM~1μM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
ANAPC2 |
| Alternative Names |
Anaphase Promoting Complex Subunit 2; APC2; Anaphase-Promoting Complex Subunit 2; Cyclosome Subunit 2; KIAA1406; ANAPC2 |
| Gene ID |
29882 |
| UniProt ID |
Q9UJX6 |
| Target Overview |
A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins, which may also be involved in ubiquitin-mediated degradation. |
| Chemical Modification |
DNA/RNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
