This product is an aptamer which binds to the ANAPC4 with an affinity of 1nM~1μM.
Target Category | Protein |
Target | ANAPC4 |
Alternative Names | Anaphase Promoting Complex Subunit 4; APC4; Anaphase-Promoting Complex Subunit 4; Cyclosome Subunit 4; ANAPC4 |
Gene ID | 29945 |
UniProt ID | Q9UJX5 |
Target Overview | A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The exact function of this gene product is not known. Two transcript variants encoding different isoforms have been found for this gene. |
Chemical Modification | DNA/RNA |
Length | 20-80 nt |
Affinity (Kd) | 1nM~1μM |
Binding Conditions/Buffer | PBS; buffer system with Serum; other |