Anti-ANKK1 Aptamer(Cat#: CTApt-2439)

This product is an aptamer which binds to the ANKK1 with an affinity of 1nM~1μM.

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3’ Modification
 
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Summary

Specifications
Target Category Protein
Target ANKK1
Alternative Names Ankyrin Repeat And Kinase Domain Containing 1; X-Kinase; Ankyrin Repeat And Protein Kinase Domain-Containing Protein 1; Protein Kinase PKK2; Sugen Kinase 288; EC 2.7.11.1; SgK288; PKK2; EC 2.7.11; SGK288; ANKK1
Gene ID 255239
UniProt ID Q8NFD2
Target Overview The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene is closely linked to DRD2 gene (GeneID:1813) on chr 11, and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of ANKK1 gene (PMIDs: 18621654, 15146457), where it causes a nonconservative amino acid substitution. It is not clear if this gene plays any role in neuropsychiatric disorders previously associated with Taq1A RFLP.
Chemical Modification DNA/RNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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