This product is an aptamer which binds to the ANKK1 with an affinity of 1nM~1μM.
Target Category | Protein |
Target | ANKK1 |
Alternative Names | Ankyrin Repeat And Kinase Domain Containing 1; X-Kinase; Ankyrin Repeat And Protein Kinase Domain-Containing Protein 1; Protein Kinase PKK2; Sugen Kinase 288; EC 2.7.11.1; SgK288; PKK2; EC 2.7.11; SGK288; ANKK1 |
Gene ID | 255239 |
UniProt ID | Q8NFD2 |
Target Overview | The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene is closely linked to DRD2 gene (GeneID:1813) on chr 11, and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of ANKK1 gene (PMIDs: 18621654, 15146457), where it causes a nonconservative amino acid substitution. It is not clear if this gene plays any role in neuropsychiatric disorders previously associated with Taq1A RFLP. |
Chemical Modification | DNA/RNA |
Length | 20-80 nt |
Affinity (Kd) | 1nM~1μM |
Binding Conditions/Buffer | PBS; buffer system with Serum; other |