Anti-APLP2 Aptamer(Cat#: CTApt-2455)
This product is an aptamer which binds to the APLP2 with an affinity of 1nM~1μM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
APLP2 |
| Alternative Names |
Amyloid Beta Precursor Like Protein 2; APPH; Amyloid Beta (A4) Precursor-Like Protein 2; CDEI Box-Binding Protein; Amyloid-Like Protein 2; APLP-2; APPL2; CDEBP; Amyloid Precursor Protein Homolog HSD-2; Testicular Tissue Protein Li 23; Amyloid Protein Homolog; APLP2 |
| Gene ID |
334 |
| UniProt ID |
Q06481 |
| Target Overview |
This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. |
| Chemical Modification |
DNA/RNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
