Anti-ARAP2 Aptamer(Cat#: CTApt-1317)
This product is an aptamer which binds to the ARAP2 with an affinity of 1nM~1μM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
ARAP2 |
| Alternative Names |
ArfGAP With RhoGAP Domain, Ankyrin Repeat And PH Domain 2; Arf-GAP With Rho-GAP Domain, ANK Repeat And PH Domain-Containing Protein 2; Centaurin-Delta-1; CENTD1; PARX; Arf And Rho GAP Adapter Protein 2; Centaurin, Delta 1; Protein PARX; KIAA0580; Cnt-D1; ARAP2 |
| Gene ID |
116984 |
| UniProt ID |
Q8WZ64 |
| Target Overview |
The protein encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. The protein is a phosphatidylinositol (3,4,5)-trisphosphate-dependent Arf6 GAP that binds RhoA-GTP, but it lacks the predicted catalytic arginine in the RHO-GAP domain and does not have RHO-GAP activity. The protein associates with focal adhesions and functions downstream of RhoA to regulate focal adhesion dynamics. |
| Chemical Modification |
DNA/RNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
