This product is an aptamer which binds to the ARFGEF1 with an affinity of 1nM~1μM.
Target Category | Protein |
Target | ARFGEF1 |
Alternative Names | ADP Ribosylation Factor Guanine Nucleotide Exchange Factor 1; Brefeldin A-Inhibited Guanine Nucleotide-Exchange Protein 1; ARFGEP1; BIG1; ADP-Ribosylation Factor Guanine Nucleotide-Exchange Factor 1 (Brefeldin A-Inhibited) ; P200 ARF Guanine Nucleotide Exchange Factor; P200; ADP-Ribosylation Factor Guanine Nucleotide-Exchange Factor 1; Brefeldin A-Inhibited GEP 1; P200 ARF-GEP1; DKFZP434L057; ARFGEF1 |
Gene ID | 10565 |
UniProt ID | Q9Y6D6 |
Target Overview | ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP. It contains a Sec7 domain, which may be responsible for guanine-nucleotide exchange activity and also brefeldin A inhibition. |
Chemical Modification | DNA/RNA |
Length | 20-80 nt |
Affinity (Kd) | 1nM~1μM |
Binding Conditions/Buffer | PBS; buffer system with Serum; other |