Anti-ARHGEF18 Aptamer(Cat#: CTApt-1279)
This product is an aptamer which binds to the ARHGEF18 with an affinity of 1nM~1μM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
ARHGEF18 |
| Alternative Names |
Rho/Rac Guanine Nucleotide Exchange Factor 18; Rho/Rac Guanine Nucleotide Exchange Factor (GEF) 18; P114RhoGEF; 114 KDa Rho-Specific Guanine Nucleotide Exchange Factor; Rho-Specific Guanine Nucleotide Exchange Factor P114; Rho Guanine Nucleotide Exchange Factor 18; Septin-Associated RhoGEF; P114-RhoGEF; SA-RhoGEF; KIAA0521; P114-Rho-GEF; EC 3.4.24; ARHGEF18; MGC15913; EC 3.6.1; RP78 |
| Gene ID |
23370 |
| UniProt ID |
Q6ZSZ5 |
| Target Overview |
Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GEF family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified. |
| Chemical Modification |
DNA/RNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
