Anti-ATAD3A Aptamer(Cat#: CTApt-2551)
This product is an aptamer which binds to the ATAD3A with an affinity of 1nM~1μM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
ATAD3A |
| Alternative Names |
ATPase Family AAA Domain Containing 3A; ATPase Family AAA Domain-Containing Protein 3A; FLJ10709; PHRINL; ATAD3A; HAYOS |
| Gene ID |
55210 |
| UniProt ID |
Q9NVI7 |
| Target Overview |
This gene encodes a ubiquitously expressed mitochondrial membrane protein that contributes to mitochondrial dynamics, nucleoid organization, protein translation, cell growth, and cholesterol metabolism. This gene is a member of the ATPase family AAA-domain containing 3 gene family which, in humans, includes two other paralogs. Naturally occurring mutations in this gene are associated with distinct neurological syndromes including Harel-Yoon syndrome. High-level expression of this gene is associated with poor survival in breast cancer patients. A homozygous knockout of the orthologous gene in mice results in embryonic lethality at day 7.5 due to growth retardation and defective development of the trophoblast lineage. Alternative splicing results in multiple transcript variants. |
| Chemical Modification |
DNA/RNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
