Anti-ATF2 Aptamer(Cat#: CTApt-2241)
This product is an aptamer which binds to the ATF2 with an affinity of 1nM~1μM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
ATF2 |
| Alternative Names |
Activating Transcription Factor 2; HB16; Cyclic AMP-Dependent Transcription Factor ATF-2; Cyclic AMP-Responsive Element-Binding Protein 2; CAMP Response Element-Binding Protein CRE-BP1; CAMP-Dependent Transcription Factor ATF-2; Histone Acetyltransferase ATF2; CRE-BP1; CREB-2; CREB2; TREB7; Activating Transcription Factor 2 Splice Variant ATF2-Var2; CAMP Responsive Element Binding Protein 2, Formerly; CAMP Responsive Element Binding Protein 2; CAMP-Responsive Element-Binding Protein 2; EC 2.3.1.48; CREBP1; ATF2 |
| Gene ID |
1386 |
| UniProt ID |
P15336 |
| Target Overview |
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene. |
| Chemical Modification |
DNA/RNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
