This product is an aptamer which binds to the ATP1B4 with an affinity of 1nM~1μM.
Target Category | Protein |
Target | ATP1B4 |
Alternative Names | ATPase Na+/K+ Transporting Family Member Beta 4; ATPase, Na+/K+ Transporting, Beta 4 Polypeptide; X/Potassium-Transporting ATPase Subunit Beta-M; Na,K-ATPase Beta M-Subunit; Protein ATP1B4; BetaM; ATPase, (Na+)/K+ Transporting, Beta 4 Polypeptide; X,K-ATPase Beta-M Subunit; X,K-ATPase Subunit Beta-M; ATP1B4 |
Gene ID | 23439 |
UniProt ID | Q9UN42 |
Target Overview | This gene has been found in all vertebrate genomes sequenced to date. However, this gene has undergone a change in function in placental mammals compared to other species. Specifically, in fish, avian, and amphibian species, this gene encodes plasma membrane-bound beta-subunits of Na,K-ATPase. In placental mammals, the encoded protein interacts with the nuclear transcriptional coregulator SKIP and may be involved in the regulation of TGF-beta signaling. Two transcript variants encoding different isoforms have been found for this gene. |
Chemical Modification | DNA/RNA |
Length | 20-80 nt |
Affinity (Kd) | 1nM~1μM |
Binding Conditions/Buffer | PBS; buffer system with Serum; other |