Anti-ATP1B4 Aptamer(Cat#: CTApt-2264)

This product is an aptamer which binds to the ATP1B4 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target ATP1B4
Alternative Names ATPase Na+/K+ Transporting Family Member Beta 4; ATPase, Na+/K+ Transporting, Beta 4 Polypeptide; X/Potassium-Transporting ATPase Subunit Beta-M; Na,K-ATPase Beta M-Subunit; Protein ATP1B4; BetaM; ATPase, (Na+)/K+ Transporting, Beta 4 Polypeptide; X,K-ATPase Beta-M Subunit; X,K-ATPase Subunit Beta-M; ATP1B4
Gene ID 23439
UniProt ID Q9UN42
Target Overview This gene has been found in all vertebrate genomes sequenced to date. However, this gene has undergone a change in function in placental mammals compared to other species. Specifically, in fish, avian, and amphibian species, this gene encodes plasma membrane-bound beta-subunits of Na,K-ATPase. In placental mammals, the encoded protein interacts with the nuclear transcriptional coregulator SKIP and may be involved in the regulation of TGF-beta signaling. Two transcript variants encoding different isoforms have been found for this gene.
Chemical Modification DNA/RNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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