Anti-ATP8B1 Aptamer(Cat#: CTApt-2463)
This product is an aptamer which binds to the ATP8B1 with an affinity of 1nM~1μM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
ATP8B1 |
| Alternative Names |
ATPase Phospholipid Transporting 8B1; ATPase, Class I, Type 8B, Member 1; ATPIC; PFIC; ATPase, Aminophospholipid Transporter, Class I, Type 8B, Member 1; P4-ATPase Flippase Complex Alpha Subunit ATP8B1; Familial Intrahepatic Cholestasis Type 1; Phospholipid-Transporting ATPase IC; FIC1; Probable Phospholipid-Transporting ATPase IC; ATPase Class I Type 8B Member 1; E1-E2 ATPase; EC 3.6.3.1; EC 7.6.2.1; EC 3.6.3; ATP8B1; PFIC1; BRIC; ICP1 |
| Gene ID |
5205 |
| UniProt ID |
O43520 |
| Target Overview |
This gene encodes a member of the P-type cation transport ATPase family, which belongs to the subfamily of aminophospholipid-transporting ATPases. The aminophospholipid translocases transport phosphatidylserine and phosphatidylethanolamine from one side of a bilayer to another. Mutations in this gene may result in progressive familial intrahepatic cholestasis type 1 and in benign recurrent intrahepatic cholestasis. |
| Chemical Modification |
DNA/RNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
