Anti-BCL3 aptamer(Cat#: CTApt-1867)
This product is an aptamer which binds to the BCL3 with an affinity of 1nM~1μM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
BCL3 |
| Alternative Names |
BCL3 Transcription Coactivator; Chronic Lymphatic Leukemia Protein; B-Cell Lymphoma 3-Encoded Protein; B-Cell Leukemia/Lymphoma 3; B-Cell Lymphoma 3 Protein; B Cell CLL/Lymphoma 3; Proto-Oncogene BCL3; D19S37; BCL-3; BCL4; BCL3, Transcription Coactivator; BCL3 |
| Gene ID |
602 |
| UniProt ID |
P20749 |
| Target Overview |
This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. |
| Chemical Modification |
DNA/RNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
