Anti-BIK aptamer(Cat#: CTApt-1744)
This product is an aptamer which binds to the BIK with an affinity of 1nM~1μM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
BIK |
| Alternative Names |
BCL2 Interacting Killer; NBK; BCL2-Interacting Killer (Apoptosis-Inducing) ; Bcl-2-Interacting Killer; Apoptosis Inducer NBK; Natural Born Killer; BIP1; BP4; Apoptosis-Inducing NBK; BIK |
| Gene ID |
638 |
| UniProt ID |
Q13323 |
| Target Overview |
The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins. |
| Chemical Modification |
DNA/RNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
