This product is an aptamer which binds to the Acute lymphoblastic leukemia (CCRF-CEM) with an affinity of <1 nM.
Target Category | Cell |
Target | Acute lymphoblastic leukemia (CCRF-CEM) |
Chemical Modification | DNA |
Length | 40-60 nt |
Affinity (Kd) | <1 nM |
Binding Conditions/Buffer | Binding buffer: 0.1mg/ml yeast tRNA and 1 mg/ml BSA into wash buffer (4.5g/L glucose, 5 mM MgCl2 in Dulbecco's PBS with CaCl2 and MgCl2). |
GC Content | 0.5122 |
Molecular Weight | 12634.26 g/mole |
Extinction Coefficient | 397600 L/(mole·cm) |
nmoles/OD260 | 2.52 |
It greatly expanded the scope of our experimentsExcellentThe anti-CCRF-CEM aptamer's compatibility with various detection methods and imaging techniques made it a versatile choice for our multidimensional analyses.
Worked exceptionally well in our experimentsExcellentThis aptamer significantly improved the accuracy of our cell-based assays. Its high binding specificity and minimal background noise allowed us to detect subtle differences in cell populations, contributing to the precision of our results.
The results were outstandingExcellentWe integrated this aptamer into our flow cytometry experiments. The clear discrimination between target and non-target cells contributed to the success of our immunophenotyping studies.