This product is an aptamer which binds to the HIV-1 Nuceocapsid with an affinity of <20 nM.
Target Category | Protein |
Target | HIV-1 Nuceocapsid |
Chemical Modification | RNA |
Length | 20-40 nt |
Affinity (Kd) | <20 nM |
Binding Conditions/Buffer | Binding Buffer (50 mM Tris, pH 7.5, 100 mM NaCl, 1 mM MgCl2, 30 µM ZnCl and 10 mM DTT) SSC buffer (17.5 mM sodium citrate (pH 7.0), 150 mM sodium chloride) |
GC Content | 0.575 |
Molecular Weight | 12814.65 g/mole |
Extinction Coefficient | 381200 L/(mole·cm) |
nmoles/OD260 | 2.62 |
Recommend it to other diagnostic companies and researchersExcellentAs a diagnostic company developing tests for HIV detection, we have found the HIV-1 nucleocapsid aptamer from Creative Biolabs to be an indispensable reagent. Its ability to selectively bind to the nucleocapsid protein of HIV-1 with high affinity and specificity has allowed us to design highly sensitive and accurate assays for detecting the virus in patient samples.
An outstanding tool for studying the structure and function of the HIV-1 nucleocapsid proteinExcellentIts high specificity and affinity for the protein have allowed us to isolate and characterize the protein in complex mixtures, enabling us to gain new insights into its role in HIV-1 replication.
We are very satisfied with the performance of this aptamerExcellentThe aptamer's high sensitivity and specificity for the nucleocapsid protein have allowed us to design biosensors that can detect the virus in blood, serum, and other bodily fluids with great accuracy and speed.